Restriction maps of the regions coding for methicillin and tobramycin resistances on chromosomal DNA in methicillin-resistant staphylococci.

نویسندگان

  • K Ubukata
  • R Nonoguchi
  • M Matsuhashi
  • M D Song
  • M Konno
چکیده

Chromosomal BamHI DNA fragments containing both the mecA gene encoding the penicillin-binding protein responsible for methicillin resistance and the aadD gene encoding 4',4"-adenylyltransferase responsible for tobramycin resistance were cloned from three methicillin- and tobramycin-resistant strains of Staphylococcus aureus and one strain of Staphylococcus epidermidis. Physical maps of the fragments were similar, suggesting their unique origin.

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عنوان ژورنال:
  • Antimicrobial agents and chemotherapy

دوره 33 9  شماره 

صفحات  -

تاریخ انتشار 1989